Hesire was a high official who lived during the reign of Netjerikhet (Dosjer) 2686 BC to 2613 BC . His tutelary informs us of the many offices he had held during his life. Thus he was the 'overseer of the royal scribes', at the head of the royal administration of Djoser. His most spectacular title, however, was that of the 'greatest (or chief ?)of physicians and dentists'. It is not entirely clear whether this title infers that Hesire himself was honored as the greatest of physicians and dentists, or rather that he was merely responsible for the administration of physicians and dentists. But whatever the case, the distinction between 'physicians' and 'dentists' in his tutelary does show a high degree of medical specialization at this early stage of the history of Ancient Egypt..